Tamoxifen has rarely caused very serious (possibly fatal) strokes, blood clots in the lungs/legs, and cancer of the uterus. If you are taking tamoxifen to reduce the risk of breast cancer, or if your cancer is limited to the milk ducts (ductal carcinoma in situ-DCIS), then discuss the benefits and risks of taking this medication with your doctor. However, if you are taking tamoxifen to treat breast cancer, then the benefits of taking tamoxifen are greater than the risks of side effects. Seek immediate medical attention if you develop symptoms of a stroke or blood clots in the lungs/legs, such as weakness on one side of the body, slurred speech, sudden vision changes, confusion, shortness of breath, chest pain, or calf pain/swelling. Tell your doctor right away if you develop symptoms of cancer of the uterus, such as unusual changes in your monthly period (e.g., amount or timing of bleeding), unusual vaginal discharge, or pain/pressure below your "belly button" (navel). Show More Tamoxifen is used to treat breast cancer that has spread to other parts of the body (metastatic breast cancer), to treat breast cancer in certain patients after surgery and radiation therapy, and to reduce the chances of breast cancer in high-risk patients. This medication can block the growth of breast cancer. It works by interfering with the effects of estrogen in the breast tissue. Nolvadex is a selective estrogen receptor module (SERM). Many liquid forms or nolvadex go by the name “tamoxifen citrate” rather than “liquid nolvadex.” Sometimes it's hard to know if you need a SERM such as Nolvadex or if you need an Aromatase Inhibitor. It prevents estrogen from binding to receptors, specifically in the breast tissue. Nolvadex simply keeps estrogen at bay but from occurring. This DOES NOT MEAN that estrogen levels do not still become elevated in the body from certain steroids, specifically estrogenic compounds that cause gynocomastia and water retention. This is where much of the confusion comes when choosing between a Selective Estrogen Receptor Module (SERM) or an Aromatase Inhibitor (AI). Some of my suggestions on proactive forms of estrogen suppression and post cycle recovery may seem contradictory. What you need to understand is that what I would suggest to someone is based off of two things; #1- What compounds they're using and #2- How much they're using For example, most men using 25-50mg/day of Dbol will find that nolvadex is enough to keep side effects such as gynecomastia away. A small percentage of users would probably need something stronger such as an aromatase inhibitor. There are many studies that show nolvadex to be inferior to aromatase inhibitors DURING CYCLE and at suppression of estrogen, BUT SUPERIOR in stimulating the HPTA axis and restoring testicular function/natural testosterone production. 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