Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet. The effectiveness of orlistat in promoting weight loss is definite but modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2–3 kilograms (4.4–6.6 lb) more than those not taking the drug over the course of a year. Orlistat also modestly reduces blood pressure and appears to prevent the onset of type 2 diabetes, whether from the weight loss itself or other effects. It reduces the incidence of diabetes type II in people who are obese around the same amount that lifestyle changes do. Benefits aside, however, orlistat is notorious for its gastrointestinal side effects (sometimes referred to as treatment effects), which can include steatorrhea (oily, loose stools). Xenical (Orlistat) is a weight loss aid used in combination with a low-calorie diet and doctor-approved exercise. It also helps to continue maintaining weight following weight loss. Orlistat is used in patients with a certain weight who may also have high blood pressure, diabetes, high cholesterol, or heart disease. Orlistat is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the fat you eat from being absorbed and disgested. This undigested fat is then removed in your bowel movements (BM). Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your health care provider. It is usually taken 3x /day with each meal that contains fat. Before taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. Follow your doctor’s instructions when taking this medication. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Prednisone asthma side effects Buy doxycycline in us Zoloft and weight gain Orlistat is a prescription medication and this article will provide you with all of the information you need to understand what it is, what it does, the potential side effects, and if it is for you. What Is Orlistat? Orlistat is known as a drug designed to specifically combat obesity, also known by the trade name Xenical. Xenical 120mg hard capsules. Orlistat. Read all of this leaflet carefully before you start taking. If you get any of the side effects, talk to your doctor or pharmacist. Dec 26, 2012. The serious side effects tied to Xenical and Alli are only the latest to emerge. In 2010, the weight loss drug Meridia sibutramine was taken off. (orlistat); however, not everyone who takes the drug will experience problems. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider. Xenical has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and are then compared to side effects that occur in another group of people not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine. Many of the side effects of Xenical that affect the digestive tract can be avoided or reduced by decreasing the amount of fat in your diet. Because Xenical decreases the absorption of fat, more fat stays in the digestive tract, causing many of the bothersome and sometimes embarrassing side effects. You are more likely to experience these problems if you eat too much fat. 120 mg TID show no additional benefit OTC (Alli): Up to 60 mg PO q8hr with each fat containing meal Only effective as an adjunct to caloric restriction, increased physical activity, and behavioral modification Also see Administration and Cautions (drug interaction overview) Flatulence Fatty/oily stool Increased defecation Fecal incontinence Nausea Vomiting Reduced absorption of fat soluble vitamins and beta-carotene Liver failure Oxalate nephropathy Leukocytoclastic vasculitis If a meal is missed or contains no fat, dose should be omitted Daily fat intake (30% of calories), carbohydrate, and protein should be evenly distributed over 3 main meals Note: Multivitamin supplement (including vit A, D, E, K) is recommended Postmarketing reports of severe liver injury with hepatocellular necrosis or acute hepatic failure with some cases resulting in liver transplant or death History of hyperoxaluria or calcium oxalate nephrolithiasis; cases of oxalate nephrolithiasis and oxalate nephropathy with renal failure have been reported Substantial weight loss can increase risk of cholelithiasis Exclude organic causes of obesisty (eg, hypothyroidism), before prescribing therapy May increase gastrointestinal events when taking a diet high on fat ( Pregnancy Category: X; weight loss offers no potential benefit to a pregnant woman and may result in fetal harm; a minimum weight gain, and no weight loss, is currently recommended for all pregnant women, including those who are already overweight or obese Lactation: Not recommended; not known if orlistat is distributed in breast milk Take with each fat-containing meal (during or up to 1 hr after the meal) The patient should be on a nutritionally balanced, reduced-calorie diet that contains ~30% of calories from fat Daily intake of fat, carbohydrate, and protein should be distributed over 3 main meals If a meal is occasionally missed or contains no fat, omit the orlistat dose The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. Orlistat xenical side effects Xenical orlistat dose, indications, adverse effects, interactions. from., XENICAL, INN-orlistat Order levitraCialis indigestion cureMetformin does whatViagra coupons from pfizerPrice for amoxicillin Jun 1, 2015. Orlistat is sold as Xenical in a prescription-strength formulation, and as. advised people to avoid orlistat because of its side effects including. Alli Orlistat - Side Effects, Dosage, Interactions - Drugs. Orlistat May Cause Permanent Liver and Kidney Damage - Dr. Mercola. Orlistat - Search Livertox Database. Orlistat side effects Like all medicines, orlistat can cause uncomfortable side effects. These are likely to be more pronounced through the use of Xenical, but side effects can also occur in the over-the-counter version of orlistat. An Introduction to Xenical Side Effects As with any medicine, side effects are possible with Xenical ® orlistat ; however, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well. To negate the side effects of orlistat, take a high-quality multivitamin two hours before or after taking the drug. In a study conducted at the University of Rhode Island, Professor Bingfang Yan found that orlistat also limits an enzyme called carboxylesterase-2.