Kathryn Meininger began writing and publishing poetry in 1967. She was co-founder and editor of the professional magazine "Footsteps" and began writing articles online in 2010. She earned a Doctor of Podiatric Medicine from Temple University School of Podiatric Medicine and a Bachelor of Arts in biology from William Paterson University. View Full Profile Valtrex can affect kidney function, resulting in kidney failure. Valtrex, taken orally or intravenously, can lead to renal toxicity and renal failure in some who take the drug long term. According to the American Social Health Association, Valtrex converts to acyclovir as it is metabolized, and may crystallize out within the renal tubules, leading to renal toxicity and failure. Inadequate hydration can increase the chances for kidney failure, so drink plenty of water to keep your kidneys hydrated while taking Valtrex. And although recurrent outbreaks can occur while taking valacyclovir, they are rare -- and monthly is unheard of. It is possible your HSV has become resistant to the drug, but that's quite rare as well. As for valacyclovir side effects, you needn't worry. It isn't true that long term effects are unknown; although there have been few if any formal research studies, the day-to-day experience of herpes experts is that it is an exceedingly safe drug with no known toxicity, even taken years on end. The official prescribing information for valacyclovir indicates a 1% chance of minor abnormalities of liver function in people taking valacyclovir, which was slightly higher than 0.5% for placebo. That difference was not statistically significant and there is no suggestion even for routine liver tests in people taking the drug. Here is a link to the official prescribing information about the drug, as approved by the US Food and Drug Administration: That is why recurrent outbreaks reappear a few weeks after you stop the drug. Where to buy finasteride (proscar propecia) Cialis 90 day supply Buy bactrim antibiotic Uses. Valacyclovir is used to treat infections caused by certain types of viruses. In children, it is used to treat cold sores around the mouth caused by herpes simplex and chickenpox caused by. Valacyclovir is a nucleoside analogue antiviral agent and prodrug of acyclovir. and absence of renal dysfunction were atypical for acetaminophen toxicity. Valacyclovir is available as capsules of 500 mg and 1000 mg generically and under the brand name of Valtrex. The usually recommended dose in adults is 500 to 1000 mg once or twice daily. Side effects are uncommon, but include headache, dizziness and gastrointestinal upset. It slows the growth and spread of the herpes virus to help the body fight the infection. Valtrex is used to treat infections caused by herpes viruses, including genital herpes, cold sores, and shingles (herpes zoster) in adults. Valtrex is used to treat cold sores in children who are at least 12 years old, or chickenpox in children who are at least 2 years old. Valtrex will not cure herpes and will not prevent you from spreading the virus to other people. However, this medicine can lessen the symptoms of an infection. Valtrex may also be used for purposes not listed in this medication guide. Before taking Valtrex, tell your doctor if you have HIV/AIDS, a weak immune system, kidney disease (or if you are on dialysis), or if you have had a kidney or bone marrow transplant. Our free Discount Rx savings card can help you and your family save money on your prescriptions. This card is accepted at all major chain pharmacies, nationwide. Enter your name and email address to receive your free savings card. Our free Discount Rx savings card can help you and your family save money on your prescriptions. This card is accepted at all major chain pharmacies, nationwide. Enter your name and email address to receive your free savings card. (valacyclovir hydrochloride) is a prescription medication that has been licensed to treat shingles, chickenpox, cold sores, and genital herpes. Valtrex toxicity Valacyclovir toxicity - MedHelp, Valacyclovir - LiverTox - NIH Buy celexa cheapBuy clomid online mexico Valtrex is the brand name for valacyclovir, an antiviral drug used to. a poison help line at 800 222-1222 in case of an overdose of Valtrex. Valtrex Valacyclovir - Side Effects, Dosage, Interactions - Drugs. Valacyclovir - Search Livertox Database. Valtrex valacyclovir Side Effects, Interactions, Uses.. Letter to the Editor. DOI 10.1016/j.nefroe.20. Open Access. Acute renal failure and severe neurotoxicity after unintentional overdose of valacyclovir in. Although this feature may confer more potent activity, it may also increase the risk of renal toxicity due to precipitation of acyclovir crystals in the renal tubules see "Crystal-induced acute kidney injury". On the other hand, the safety of high-dose oral valacyclovir, especially in immunocompromised persons, remains controversial. Toxicity and to include them in the differential diagnosis. Recognition of a. valacyclovir, 1 gram every 8 hours, with prednisone. The next day, the patient began.