This medication is used to treat the first outbreak of genital herpes infection. It is also used to treat non-life-threatening herpes infections of the skin and around the mouth (cold sores) in people with a weakened immune system. This medication does not cure herpes or prevent the infection from coming back. If this happens, wash right away with plenty of water. This medication may decrease the length of time you have pain and help the sores heal faster. Also, it does not prevent the spread of herpes to others. Begin using acyclovir as soon as symptoms of a herpes infection appear. Other antiviral medications taken by mouth may be more effective in treating these conditions. Wash your hands with soap and water before and after using this medication. Clean and dry the affected areas before applying the medication. Use a finger cot or rubber glove when applying acyclovir to prevent spreading the infection to other parts of your body and to other people. Apply enough ointment to cover all sores, usually every 3 hours, 6 times a day, or as directed by your doctor. Acyclovir is used to treat infections caused by certain types of viruses. It treats cold sores around the mouth (caused by herpes simplex), shingles (caused by herpes zoster), and chickenpox. This medication is also used to treat outbreaks of genital herpes. The viruses that cause these infections continue to live in the body even between outbreaks. In people with frequent outbreaks, acyclovir is used to help reduce the number of future episodes. Acyclovir decreases the severity and length of these outbreaks. It helps the sores heal faster, keeps new sores from forming, and decreases pain/itching. This medication may also help reduce how long pain remains after the sores heal. In addition, in people with a weakened immune system, acyclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections. 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Follow all physician's instructions and directions for use on the prescription label. Wash your hands throughly before applying the topical ointment. Use only enough to cover the area of the cold sore that is tingling or burning. Gently rub in the ointment until it is absorbed into the skin. Zovirax Cold Sore Cream has been clinically proven to be able to prevent cold sores from appearing. The cream contains the unique antiviral agent Aciclovir which prevents the cold sore virus from replicating. Zovirax Cold Sore Cream has been prescribed for over 10 years to more that 22 million patients around the world. Zovirax Cold Sore Cream has been clinically proven to be able to prevent cold sores from appearing. The cream contains the unique antiviral agent Acyclovir which prevents the cold sore virus from replicating. Zovirax Cold Sore Cream has been prescribed for over 10 years to more that 22 million patients around the world. 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