Tamoxifen is a hormone therapy drug taken by many premenopausal women after completing their initial treatments for estrogen receptor positive breast cancer. To treat the side effects of tamoxifen (such as hot flashes) and to help with depression, doctors often prescribe antidepressants. Yet many antidepressants can interfere, or completely cancel out, the benefits of tamoxifen. Once a woman is finished with the primary treatment of breast cancer, with therapies such as surgery, chemotherapy, and radiation therapy, she may need to take tamoxifen. For women who have estrogen receptor positive tumors, hormone therapy can reduce the risk of the cancer coming back (recurrence) by around 50 percent. The choice of medication depends on menopausal status. If a woman is premenopausal, tamoxifen is usually the drug of choice. (For those who are postmenopausal, or who are premenopausal but have received ovarian suppression therapy, an aromatase inhibitor is usually used instead). Current oncology guidelines clearly advise caution on the coadministration of tamoxifen with medications that decrease the formation of active tamoxifen metabolites. Medications classified as strong inhibitors of tamoxifen biotransformation reduce plasma concentrations of active metabolites by as much as 64%. Although genetic polymorphisms that adversely affect CYP2D6 enzyme function can reduce the formation of active tamoxifen metabolites by as much as 74%, San Antonio Breast Cancer Symposium Recommendations discourage testing for CYP2D6 polymorphisms. The standard of care is clear: Drugs that interfere with the formation of active tamoxifen metabolites are important to consider and relevant to patient care, but genetic polymorphisms that do the same are not. Based on the data available to date, the question of whether CYP2D6 polymorphisms impact breast cancer survival and recurrence has not been fully answered. Definitive prospective research has not been completed, and there are possible deficiencies in the studies used to establish current guidelines. It is important for clinicians to understand both treatment guidelines and their possible deficiencies in order to best meet the individual needs and concerns of their patients. Drugs that interfere with the biotransformation of tamoxifen into active metabolites through cytochrome P450 enzymes are classified as significant interactants, and caution is advised about coadministration of these drugs with tamoxifen. Metoprolol names Sildenafil risks Inderal xl 120 mg Cialis e20 TAMOXIFEN REVIEWS. Below are the reviews of athletes and patients taking Tamoxifen-containing remedy. Nora, 28 years old In 2015, diagnosed with breast cancer of the 2nd degree. After the operation to remove the breast, and after the course of radiotherapy, the doctor prescribed Nolvadex Tamoxifen. Encourage patients taking tamoxifen to avoid medications that interfere with tamoxifen metabolism. Selective serotonin reuptake inhibitors SSRIs are commonly used for tamoxifen-induced hot flashes. Soltamox is available to patients who qualify at the same co-pay cost as generic tamoxifen. Patients can download a $10 co-pay per prescription card for unlimited use. You can also read Breastcancer.org's Paying for Your Care section for information on additional types of financial assistance and cost-lowering tips. Tamoxifen Citrate tablets are effective in the treatment of metastatic breast cancer in women and men. In premenopausal women with metastatic breast cancer, tamoxifen is an alternative to oophorectomy or ovarian irradiation. Available evidence indicates that patients whose tumors are estrogen receptor positive are more likely to benefit from tamoxifen therapy. Tamoxifen Citrate tablets are indicated for the treatment of node-positive breast cancer in women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation. In some tamoxifen adjuvant studies, most of the benefit to date has been in the subgroup with four or more positive axillary nodes. Tamoxifen Citrate tablets are indicated for the treatment of axillary node-negative breast cancer in women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation. The estrogen and progesterone receptor values may help to predict whether adjuvant tamoxifen therapy is likely to be beneficial. Generic drugs usually cost less than a brand-name drug. Tamoxifen oral tablet is only available as a generic drug. Tamoxifen is used to treat and reduce the risk of certain types of breast cancer. Tamoxifen belongs to a group of drugs called antiestrogens. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Antiestrogens work by blocking the effects of the hormone estrogen in the body. Tamoxifen reviews patients Tamoxifen for breast cancer Soltamox. Tamoxifen. - Patient, Tamoxifen and CYP2D6 Natural Medicine Journal Buy tretinoin with paypalZoloft grapefruit juiceAmoxil 125Metformin elderlyAmoxicillin in cats Find patient medical information for Tamoxifen Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Tamoxifen Oral Uses, Side Effects, Interactions, Pictures. -. Tamoxifen Uses, Side Effects, and More -. Tamoxifen Wiki Everipedia. Tamoxifen and raloxifene have been shown to reduce the risk breast cancer, but they can have their own risks and side effects. Tamoxifen and raloxifene are the only drugs that are approved in the US to help lower the risk of breast cancer, although for some women, drugs called aromatase inhibitors might be an option as well. Повышенная чувствительность к Tamoxifen Citrate является противопоказанием. Кроме того, препарат Tamoxifen Citrate запрещено принимать при наличии у вас следующих состояний Tamoxifen oral tablet is used to treat and help prevent breast cancer. Learn about side effectsTamoxifen oral tablet is only available as a generic drug. Generic drugs usually cost less than a.