Sertraline is used for a number of conditions, including major depressive disorder (MDD), obsessive–compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder, and social anxiety disorder (SAD). The comparative efficacy of sertraline and TCAs for melancholic depression has not been studied. A 1998 review suggested that, due to its pharmacology, sertraline may be more efficacious than other SSRIs and equal to TCAs for the treatment of melancholic depression. A meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with unipolar MDD. Sertraline used for the treatment of depression in elderly (older than 60) patients was superior to placebo and comparable to another SSRI fluoxetine, and TCAs amitriptyline, nortriptyline (Pamelor) and imipramine. Sertraline had much lower rates of adverse effects than these TCAs, with the exception of nausea, which occurred more frequently with sertraline. In addition, sertraline appeared to be more effective than fluoxetine or nortriptyline in the older-than-70 subgroup. placebo in elderly patients showed a statistically significant (that is, unlikely to occur by chance), but clinically very modest improvement in depression and no improvement in quality of life. A meta-analysis on SSRIs and SNRIs that look at partial response (defined as at least a 50% reduction in depression score from baseline) found that sertraline, paroxetine and duloxetine were better than placebo. If you are considering taking an antidepressant, you may be concerned about how long you’ll need to stay on it. Even if you feel that it will help treat your depression, you may not like taking any medicine if you can help it. You may wonder about side effects or long-term effects of taking a drug that alters brain chemistry. If you’re already taking a medication for depression, you might be wondering about when to stop. If your mood and outlook on life have gotten brighter, do you really need to continue taking an antidepressant? In general, doctors recommend that people stay on an antidepressant at least one year to experience the full benefits. Beyond that, when -- and whether -- you should to go off depression medication is a personal choice that requires serious thought. Why does tadafil have to be taken under the tongue Is cialis good for you OverviewMedical usesContraindicationsSide effectsOverdoseInteractions How Long Should You Take Antidepressants. and what to consider when deciding how long to take. “Antidepressants can take a few weeks to a couple of months before they take full effect. Brand name Zoloft®. Tablets 25. Do not stop taking sertraline, even when you feel better. Only your. Please refer to serious side effects for signs/symptoms. Zoloft (Sertraline) is a selective-serotonin reuptake inhibitor (SSRI) prescribed for a variety of medical conditions, including: major depressive disorder, obsessive-compulsive disorder, panic disorder, and social anxiety disorder. On occasion, Zoloft is even used off-label to help manage symptoms of premenstrual syndrome (PMS), body dysmorphic disorder, vascular headaches, and premature ejaculation. Though the effectiveness of Zoloft is generally regarded as analogous to other antidepressant medications, one meta-analysis published in The Lancet (2009) reported that Zoloft may be superior to a majority of serotonergic antidepressants in terms of efficacy and tolerability among adults with major depressive disorder. Because Zoloft is an effective treatment option for numerous conditions, and is sold for a low cost due to its generic status (approximately $1.50 for a monthly prescription) – it remains a popular medication. In the event that you’ve been prescribed Zoloft to treat a medical condition, you might be wondering how long it’ll take for the medication to work or fully “kick in.” In fact, you’ve probably been Googling how long it took for Zoloft to start working and are finding all sorts of mixed reviews: some suggesting that it works rapidly (immediately) and others noting that it takes weeks to reach full effect. Although Zoloft starts working immediately in terms of exerting a neurophysiologic effect, it may take weeks for the medication to facilitate a desired or clinically relevant therapeutic effect. That said, some users may notice that the medication starts working in a short amount of time (e.g. within hours or days of initiating treatment), whereas others may report that the medication takes several weeks to start working. Does the medication work right away – or will you need to take it for 4 to 6 weeks to derive therapeutic benefit? It's also used to treat obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (PMDD) and social anxiety disorder. Zoloft, an oral antidepressant pill made of compressed crystalline powder, is usually prescribed to first-time users in a 50-milligram-per-day dose for depression and PMDD and 25 milligrams per day for other disorders. Our bodies need time to adapt to the new normal created by taking a pill laced with sertraline that is designed to increase serotonin levels in the brain. Dosages can be increased with time and medical supervision up to 200 milligrams per day. Not only does this SSRI medication help the brain absorb serotonin into the blood stream more effectively, but it may actually change the makeup of the brain. It's also available in liquid form [source: RX List]. The brain needs new receptors to help absorb the additional serotonin; it builds and installs additional receptors -- a biological process that can take up to eight weeks. Within just a few hours of taking an SSRI for the first time, the levels of serotonin in the brain and bloodstream increase. So, even though Zoloft increases the levels of serotonin in our bodies nearly immediately, our brains aren't immediately equipped to absorb it [source: Crowe]. If, however, after six to eight weeks, Zoloft doesn't seem to be positively affecting your mood, anxiety -- or other condition for which it was prescribed -- it's time to alert your physician. Not every antidepressant will work the same for every person, and an estimated 50 percent of people who try an antidepressant will need to take a different brand or class before finding one that works for them. Zoloft how long to take effect How Long Does It Take For Zoloft To Work or "Kick In., How Long Should You Take Depression Medication? Order clomid pills Shawn McGrath didn't make it to the big time. An up-and-coming professional wrestler, McGrath -- known as "Badseed Shawn Osborne" -- spent years trying to. How long does it take for Zoloft to work? HowStuffWorks. Sertraline Zoloft NAMI National Alliance on Mental Illness. An Overview of Zoloft for Panic Disorder - Verywell Mind. Oct 28, 2014. Zoloft, like other drugs, is not without side effects. If you forget to take Zoloft, take your missed medicine as soon as you remember, unless it's. Find patient medical information for Zoloft Oral on WebMD including its uses, side. Take this medication regularly to get the most benefit from it. Some conditions may become worse when this drug is suddenly stopped. Also. Side Effects. Zoloft isn't only for major depression. It's also used to treat obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric.