Feeling like you're coming down with the flu lately? If you've recently discontinued an antidepressant you might actually be going through withdrawal, or what is more properly called antidepressant discontinuation syndrome (ADS). Symptoms such as fatigue, nausea, chills, and muscle aches can mirror the flu. You may even have symptoms after missing only a single dose or taking it late. Plus, the symptoms may come on several days after you stopped your medication, making it harder to link them to discontinuation as the cause. If it is flu season (October through March) you may indeed have influenza. However, flu-like symptoms occur with many infections. Prozac and Zoloft are powerful prescription medications used to treat depression and other issues. The generic version of Prozac is fluoxetine, while the generic version of Zoloft is sertraline hydrochloride. Both drugs are selective serotonin reuptake inhibitors (SSRIs). Serotonin is a naturally occurring chemical that produces a feeling of well-being. These drugs work by influencing serotonin levels in your brain. By balancing chemicals in your brain, these drugs will likely improve your mood and appetite. They can also enhance your energy levels and help you sleep better. Both medications can reduce anxiety, fear, and compulsive behaviors. Amoxicillin 400 5ml dosage Lyrica coupons 2017 Zoloft received an overall rating of 6 out of 10 stars from 1290 reviews. See what others have said about Zoloft, including the effectiveness, ease of use and side effects. Zoloft Reviews. Antidepressant discontinuation syndrome is more likely with a longer duration of treatment and a shorter half-life of the treatment drug. 66 percent or sertraline Zoloft 60 percent. This. Zoloft sertraline Paxil paroxetine. The best advice if you are planning to discontinue your antidepressant is to seek your doctor's approval and advice. When. Psychiatrists and doctors have done only a small amount of research into exploring what they call the SSRI discontinuation syndrome despite many complaints from those taking the drugs. (SSRIs are a class of compounds broadly used as antidepressants.)Before going off patent, Paxil made $11.7 billion in sales for Glaxo Smith Kline and Zoloft made $30 billion in sales for Pfizer. Both SSRI drugs continue to be sold today along with generic counterparts created post-patent by other companies. Back in 1997 the Journal of Clinical Psychiatry published a research paper that attempted to explore all the medical literature and any controlled studies on SSRI withdrawal symptoms. They did find evidence that such symptoms like “flashes in my peripheral vision and headaches”, “random flashes of split-second dizziness…like a mild electrical jolt in your brain” and “electric shock phenomena” were real and, of course, suggested further study rather than suggesting action to protect patients taking the drugs.• dizziness/vertigo • nausea • fatigue/malaise • gastrointestinal symptoms • vomiting • abdominal discomfort • agitation • insomnia • myalgias (muscle pain) • tremulousness/tremors • “electric sensations”/ • headaches • abnormal dreams • “withdrawal buzz” -intense distracting sensation within the head and disorientation or dizziness • visual hallucinations • crying spells • paresthesias -a sensation of tingling, tickling, prickling, pricking, or burning of a person’s skin One of the few controlled tests the researchers reported was done on a group of patients given Paxil for stuttering. (Why an antidepressant was given for stuttering was not explained.) Six weeks on Paxil, then half the group were taken off Paxil and half got a placebo. They discovered those coming off the drug experienced euphoria followed by aggression and suicidal impulses along with dizzyness, blurred vision, nausea lethargy and insomnia.“I’ve been taking Paxil 20mg for 12 years…a month ago I went down to 10mg and I am now down to 5mg. Most common adverse reactions (≥5% and twice placebo) in pooled placebo-controlled MDD, OCD, PD, PTSD, SAD and PMDD clinical trials were nausea, diarrhea/loose stool, tremor, dyspepsia, decreased appetite, hyperhidrosis, ejaculation failure, and decreased libido (6.1) At least 14 days must elapse between discontinuation of a monoamine oxidase inhibitor (MAOI) antidepressant and initiation of ZOLOFT. In addition, at least 14 days must elapse after stopping ZOLOFT before starting an MAOI antidepressant Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The data described below are from randomized, double-blind, placebo-controlled trials of ZOLOFT (mostly 50 mg to 200 mg per day) in 3066 adults diagnosed with MDD, OCD, PD, PTSD, SAD, and PMDD. These 3066 patients exposed to ZOLOFT for 8 to12 weeks represent 568 patient-years of exposure. The mean age was 40 years; 57% were females and 43% were males. The most common adverse reactions (≥5% and twice placebo) in all pooled placebo-controlled clinical trials of all ZOLOFT-treated patients with MDD, OCD, PD, PTSD, SAD and PMDD were nausea, diarrhea/loose stool, tremor, dyspepsia, decreased appetite, hyperhidrosis, ejaculation failure, and decreased libido (see Table 3). The following are the most common adverse reactions in trials of ZOLOFT (≥5% and twice placebo) by indication that were not mentioned previously. Zoloft discontinue Sertraline - Wikipedia, Antidepressant Discontinuation Syndrome - American Family. Metoprolol tartrate to succinate conversion Zoloft is classified an as SSRI Selective Serotonin Re-uptake Inhibitor, the most commonly used class of antidepressant. Most sources recommended to taper SSRI medications, such as Zoloft, if they have been used continually for an extended period of time. How To Stop Taking Zoloft Sertraline PharmacistAnswers. Flu-Like Symptoms When You Discontinue Antidepressants. Prozac vs. Zoloft What's the Difference? - Healthline. Sertraline Zoloft is a prescription medication indicated for the treatment of major depressive disorder and panic disorder in adults. Learn about side effects, drug interactions, dosages, warnings, and more. Before going off patent, Paxil made $11.7 billion in sales for GlaxoSmithKline and Zoloft made $30 billion in sales for Pfizer. Both SSRI drugs continue to be sold today along with generic counterparts created post-patent by other companies. Starting sertraline in a patient who is being treated with linezolid or IV methylene blue is contraindicated because of an increased risk of serotonin syndrome If linezolid or IV methylene blue must be administered, discontinue SSRI immediately and monitor for CNS toxicity; may resume 24 hr after last linezolid or methylene blue dose, or after.