Cipro iv dose

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  1. azaly New Member

    Cipro iv dose


    Cipro IV is used to treat bacterial infections in many different parts of the body. Cipro IV oral liquid and tablets are also used to treat anthrax infection after inhalational exposure. Cipro IV may mask or delay the symptoms of syphilis. Cipro IV extended-release tablets are only used to treat urinary tract infections, including acute uncomplicated pyelonephritis. Proquin® XR tablets are only used to treat uncomplicated or simple urinary tract infections (acute cystitis). Cipro IV belongs to the class of drugs known as quinolone antibiotics. It works by killing bacteria or preventing their growth. However, Cipro IV will not work for colds, flu, or other virus infections. - Опадрай белый Y-1-7000 гидроксиметилпропилцеллюлоза 2910 5ср, титана диоксид Е171, полиэтиленгликоль 400. Концентрация препарата в этих тканях выше, чем в сыворотке. Таблетки, покрытые оболочкой белого цвета, двояковыпуклые, с риской на одной стороне. Ципрофлоксацин хорошо проникает в кости, слезную жидкость, бронхиальный секрет, слюну, кожу, мышцы, плевру, брюшину, лимфу. Код АТХ J01MA02 После приема внутрь ципрофлоксацин быстро всасывается из желудочно-кишечного тракта и расределяется в тканях и жидкостях организма. Максимальная концентрация в плазме крови достигается через 1 – 1,5 ч и составляет 0,1 мкг/мл. Высокие концентрации препарата наблюдаются в легких, почках, печени, желчном пузыре, семенной жидкости, ткани предстательной железы, миндалинах, эндометрии, фаллопиевых трубах и яичниках. Накапливающаяся концентрация препарата в нейтрофилах крови в 2 – 7 раз выше, чем в сыворотке. Объем распределения в организме составляет 2 – 3,4 л/кг. В спинномозговую жидкость препарат проникает в небольшом количестве, где его концентрация составляет 6 – 10% от концентрации в сыворотке крови. Метаболизируется в печени (15 – 30%) с образованием малоактивных метаболитов (диэтилципрофлоксацин, сульфоципрофлоксацин, оксоципро-флоксацин, формилципрофлоксацин).

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    Lower Respiratory Tract Infections. Mild/moderate 500 mg PO q12hr or 400 mg IV q12hr for 7-14 days. Severe/complicated 750 mg PO q12hr or 400 mg IV q8hr. Learn about Cipro I. V. Ciprofloxacin IV may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Mg/kg body weight three times a day with a maximum of 400 mg per dose. 10 to 14 days. Ciprofloxacin should be administered by intravenous infusion.

    The NICE British National Formulary (BNF) and British National Formulary for Children (BNFc) sites are only available to users in the UK, Crown Dependencies and British Overseas Territories. If you believe you are seeing this page in error please contact us. Mild/moderate: 500 mg PO q12hr or 400 mg IV q12hr for 7-14 days Severe/complicated: 750 mg PO q12hr or 400 mg IV q8hr for 7-14 days Limitations-of-use: Reserve fluoroquinolones for patients who do not have other available treatment options for acute bacterial exacerbation of chronic bronchitis Acute uncomplicated: Immediate-release, 250 mg PO q12hr for 3 days; extended-release, 500 mg PO q24hr for 3 days Mild/moderate: 250 mg PO q12hr or 200 mg IV q12hr for 7-14 days Severe/complicated: 500 mg PO q12hr or 400 mg IV q12hr for 7-14 days Limitations-of-use: Reserve fluoroquinolones for patients who do not have other available treatment options for uncomplicated urinary tract infections Dry powder for inhalation: Orphan designation for patients with NCFB who suffer from frequent severe acute pulmonary bacterial exacerbations which lead to further inflammation, airway, and lung parenchyma damage Indication for treatment and prophylaxis of plague due to Yersinia pestis in pediatric patients from birth to 17 years of age 15 mg/kg PO q8-12hr x10-21 days; not to exceed 500 mg/dose, OR 10 mg/kg IV q8-12hr x 10-21 days; not to exceed 400 mg/dose Postexposure therapy IV: 10 mg/kg q12hr for 60 days; individual dose not to exceed 400 mg PO: 15 mg/kg q12hr for 60 days; individual dose not to exceed 500 mg Change antibiotic to amoxicillin as soon as penicillin susceptibility confirmed Nausea (3%) Abdominal pain (2%) Diarrhea (2% adults; 5% children) Increased aminotransferase levels (2%) Vomiting (1% adults; 5% children) Headache (1%) Increased serum creatinine (1%) Rash (2%) Restlessness (1%) Acidosis Allergic reaction Angina pectoris Anorexia Arthralgia Ataxia Back pain Bad taste Blurred vision Breast pain Bronchospasm Diplopia Dizziness Drowsiness Dysphagia Dyspnea Flushing Foot pain Hallucinations Hiccups Hypertension Hypotension Insomnia Irritability Joint stiffness Lethargy Migraine Nephritis Nightmares Oral candidiasis Palpitation Photosensitivity Polyuria Syncope Tachycardia Tinnitus Tremor Urinary retention Vaginitis Acute generalized exanthematous pustulosis (AGEP), erythema multiforme, exfoliative dermatitis, fixed eruption, photosensitivity/phototoxicity reaction Agitation, confusion, delirium Agranulocytosis, albuminuria, serum cholesterol and TG elevations, blood glucose disturbances, hemolytic anemia, marrow depression (life threatening), pancytopenia (life threatening or fatal outcome), potassium elevation (serum) Anaphylactic reactions (including life-threatening anaphylactic shock), serum sickness like reaction, Stevens-Johnson syndrome Anosmia, hypesthesia Constipation, dyspepsia, dysphagia, flatulence, hepatic failure (including fatal cases), hepatic necrosis, jaundice, pancreatitis Hypertonia, hypotension (postural), increased INR (in patients treated with Vitamin K antagonists), QT prolongation, torsade de pointes, ventricular arrhythmia Methemoglobinemia Myasthenia, exacerbation of myasthenia gravis, myoclonus, nystagmus, peripheral neuropathy that may be irreversible, phenytoin alteration (serum), polyneuropathy, psychosis Myalgia, tendinitis, tendon rupture, toxic epidermal necrolysis (Lyell’s Syndrome), twitching Infections: Candiduria, vaginal candidiasis, moniliasis (oral, gastrointestinal, vaginal), pseudomembranous colitis Renal calculi Vasculitis Because the risk of these serious side effects generally outweighs the benefits for patients with acute bacterial sinusitis, acute exacerbation of chronic bronchitis, and uncomplicated UTIs, that fluoroquinolones should be reserved for use in patients with these conditions who have no alternative treatment options Use in pregnancy, though generally contraindicated for all quinolones, is allowed for life-threatening situations; limited data from use of ciprofloxacin in pregnancy show no higher rate of birth defects than background Do not use oral suspension in nasogastric tube; to prepare, add microcapsules to diluent Commonly seen adverse reactions include tendinitis, tendon rupture, arthralgia, myalgia, peripheral neuropathy, and central nervous system effects (hallucinations, anxiety, depression, insomnia, severe headaches, and confusion); these reactions can occur within hours to weeks after starting therapy, including in patients of any age or without pre-existing risk factors; discontinue therapy immediately at first signs or symptoms of any serious adverse reaction; in addition, avoid use of fluoroquinolones, in patients who have experienced any serious adverse reactions associated with fluoroquinolones (see Black Box Warnings) Peripheral neuropathy: sensory or sensorimotor axonal polyneuropathy affecting small and/or large axons resulting in paresthesias, hypoesthesias, dysesthesias, and weakness reported; peripheral neuropathy may occur rapidly after initiating and may potentially become permanent In prolonged therapy, perform periodic evaluations of organ system functions (eg, renal, hepatic, hematopoietic); adjust dose in renal impairment; superinfections may occur with prolonged or repeated antibiotic therapy; discontinue use immediately if signs and symptoms of hepatitis occur Not first drug of choice in pediatrics (except in anthrax), because of increased incidence of adverse events in comparison with control subjects, including arthropathy; no data exist on dosing for pediatric patients with renal impairment (ie, Cr Cl Distributed widely throughout body; tissue concentrations often exceed serum concentrations, especially in kidneys, gallbladder, liver, lungs, gynecologic tissue, and prostatic tissue; cerebrospinal fluid (CSF) concentration is 10% in noninflamed meninges and 14-37% in inflamed meninges; crosses placenta; enters breast milk Protein bound: 20-40% Vd: 2.1-2.7 L/kg Additive: Aminophylline, amoxicillin, amoxicillin-clavulanate, amphotericin, ampicillin-sulbactam, ceftazidime, cefuroxime, clindamycin, floxacillin, heparin, piperacillin, sodium bicarbonate, ticarcillin Y-site: Aminophylline, ampicillin-sulbactam, azithromycin, cefepime, dexamethasone sodium phosphate, furosemide, heparin, hydrocortisone sodium succinate, magnesium sulfate(? ), methylprednisolone sodium succinate, phenytoin, potassium phosphates, propofol, sodium bicarbonate(? ), sodium phosphates, total parenteral nutrition formulations, warfarin Solution: Compatible with most IV fluids Additive: Amikacin, aztreonam, dobutamine, dopamine, fluconazole, gentamicin, lidocaine, linezolid, metronidazole (ready-to-use form is compatible; hydrochloride form in vial is incompatible), midazolam, potassium chloride, tobramycin Y-site: Amiodarone, calcium gluconate, clarithromycin, digoxin, diphenhydramine, dobutamine, dopamine, linezolid, lorazepam, midazolam, promethazine, quinupristin/dalfopristin, tacrolimus The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

    Cipro iv dose

    Cipro I. V. Intravenous Uses, Side Effects, Interactions, Pictures., Cipro I. V. Ciprofloxacin IV Side Effects, Interactions,

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    Cipro/Ciprofloxacin/Ciprofloxacin, Dextrose Intravenous Inj Sol 1mL, 10mg, 2-5Clinical practice guidelines suggest an initial IV dose then a 7-day oral regimen is appropriate for patients with acute. Am J Med. 1989 Nov 30;875A52S-56S. Efficacy and safety of higher-dose intravenous ciprofloxacin in severe hospital-acquired infections. Kljucar S1. Cipro IV drug information uses, indications, side effects, dosage. Compare prices for generic cipro ivCipro IV oral liquid and tablets are also used to treat anthrax infection after inhalational exposure.

     
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