Duloxetine was approved for the treatment of major depression in 2004. While duloxetine has demonstrated improvement in depression-related symptoms compared to placebo, comparisons of duloxetine to other antidepressant medications have been less successful. A 2012 Cochrane Review did not find greater efficacy of duloxetine compared to SSRIs and newer antidepressants. Additionally, the review found evidence that duloxetine has increased side effects and reduced tolerability compared to other antidepressants. It thus did not recommend duloxetine as a first line treatment for major depressive disorder, given the (then) high cost of duloxetine compared to inexpensive off-patent antidepressants and lack of increased efficacy. do not list duloxetine among the recommended treatment options. A review from the Annals of Internal Medicine lists duloxetine among the first line drug treatments, however, along with citalopram, escitalopram, sertraline, paroxetine, and venlafaxine. Duloxetine comes as capsules and is only available on prescription. It's also used to treat nerve pain, such as fibromyalgia, and can be used to treat stress urinary incontinence in women. Duloxetine can be taken by adults aged 18 years and over. For stress urinary incontenince, duloxetine can only be used by women. To make sure it's safe for you, tell your doctor if you: For depression, anxiety and nerve pain, you'll usually take duloxetine once a day. For urinary incontinence, you'll usually take duloxetine twice a day. Swallow the capsules whole with a drink of water or juice. You can take duloxetine with or without food, but it's best to take it at the same time each day. For depression, anxiety and nerve pain, duloxetine comes in 30mg and 60mg capsules. Buy propecia australia Buy cialis rx Find a comprehensive guide to possible side effects including common and rare side effects when taking Cymbalta Duloxetine Hcl for healthcare professionals and. These will often improve over the first week or two as you continue to take the medication. Sexual side effects such as problems with orgasm or ejaculatory. Duloxetine learn about side effects, dosage, special precautions, and more on MedlinePlus The following is a list of possible side-effects that may occur in medicines that contain Duloxetine. These side-effects are possible, but do not always occur. Consult your doctor if you observe any of the following side-effects, especially if they do not go away. Before using Duloxetine, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Tell your doctor if your condition persists or worsens. If you use other drugs or over the counter products at the same time, the effects of Duloxetine may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Duloxetine may interact with the following drugs and products: In case you miss a dose, use it as soon as you notice. Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed. Show More Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine side effects first week Duloxetine Side Effects, Dosage, Uses, and More, Duloxetine Cymbalta NAMI National Alliance on Mental Illness Cialis with antibioticsSertraline dosage for dogsXanax brandsFluconazole once a week Commonly reported side effects of duloxetine include asthenia, constipation, diarrhea, dizzinessSome side effects of duloxetine may occur that usually do not need medical attention. Hyponatremia tends to develop within the first few weeks of treatment range 3 to 120 days and. Duloxetine Side Effects in Detail -. Duloxetine MedlinePlus Drug Information. Cymbalta Duloxetine - Side Effects, Dosage, Interactions -.. Deadly violence broke out at a Venezuelan town near the border with Brazil over aid delivery, leaving two people dead and 17 others injured, local authorities said. Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating.2 Severe side effectsDuloxetine is recommended as a first line agent for the treatment of chemotherapy-induced neuropathy by the American Society of Clinical Oncology,9. Duloxetine is not recommended for use in children less than 7 years of age; safety and efficacy have not been established. Duloxetine is FDA-approved for use in.